Adluru, N., D. Destiche, S. Lu, S. Doran, A. Birdsill, K. Melah, O. Okonkwo, A. Alexander, N. Dowling, S. Johnson, M. Sager, and B. Bendlin. “White Matter Microstructure in Late Middle-Age: Effects of Apolipoprotein E4 and Parental Family History of Alzheimer’s Disease.”. NeuroImage. Clinical, Vol. 4, 2014, pp. 730-42.
Little is still known about the effects of risk factors for Alzheimer’s disease (AD) on white matter microstructure in cognitively healthy adults. The purpose of this cross-sectional study was to assess the effect of two well-known risk factors for AD, parental family history and APOE4 genotype.
DOI: 10.1016/j.nicl.2014.04.008
PubMed: 24936424