The Wisconsin Registry for Alzheimer’s Prevention (WRAP) is beginning a new study called the Amyloid Disclosure Study to examine how people respond to learning their amyloid PET scan results.
The study will consist of:
- Three 1.5 hour in-person/virtual visits
- Informed consent and education session
- Education session and disclosure of the beta-amyloid PET scan result
- Personalized lifestyle counseling session with a study clinician
- Three brief phone visits (30 minutes)
Study Timeline
(click timeline to view full-screen version)
Study Goals
Goal: Develop an infrastructure to support a responsible approach to Alzheimer’s disease biomarker disclosure.
Goal: Investigate personal impacts of amyloid disclosure.
Who Is Eligible?
Eligible participants for this study are those that have completed or can complete an amyloid PET scan in WRAP (or PREDICT) and are 65 or older. Today, using amyloid PET brain scans, researchers and doctors can see where and how much amyloid is present in a person’s brain. The Wisconsin Registry for Alzheimer’s Prevention (WRAP) is using brain scans to understand the role of amyloid in Alzheimer’s disease.
About Amyloid

Amyloid is a protein produced normally in the brain, but in people with Alzheimer’s disease it accumulates abnormally causing plaques that interfere with brain cell (neuron) communication. Amyloid plaques are not normal and are always found in the brains of patients with dementia due to Alzheimer’s disease. This buildup of amyloid begins many years, perhaps decades, before symptoms of memory loss appear.

Meet Our Study Team
Lindsay Clark, PhD
Position title: Principal Investigator
Email:
lrclark
Phone: (608) 263-4405
Address:
600 Highland Avenue
Madison, WI 53792
Claire Erickson, MPA
Position title: Graduate Research Assistant
Email:
cmerickson4
Address:
Wisconsin Institute for Medical Research
1111 Highland Avenue
Madison, WI 53705
Hannah Rosario, BS
Position title: Study Coordinator
Email:
hrosario
Phone: 608-890-4150
Address:
Clinical Science Center
600 Highland Avenue
Madison, WI 53792
Learn More
If you are an enrolled participant, use the links below to access study materials when instructed. (The links for these materials are password protected; your study coordinator will provide the password.)