The Alzheimer’s Disease Research Center (ADRC) and the Wisconsin Registry for Alzheimer’s Prevention (WRAP) work together to find ways to prevent, slow down, and hopefully one day cure Alzheimer Disease. Although they are different organizations, we share a common goal. Being a participant in either of these studies, you would see similarities notably during a Biomarker visit (lumbar puncture and MRI). We hope these videos can help answer any questions or concerns you may have regarding why we do them, risks associated, and overall plan for the day. If you have any study specific questions, please reach out to the necessary staff .

“At present, the most precise of the Alzheimer’s disease biomarkers are those that tell us about levels of certain proteins in the brain. Specifically, the levels of amyloid and Tau proteins and the degree of brain shrinkage. There are two methods of getting this information. The first involves a series of specialized brain images. A second method of getting amyloid, Tau, and neurodegeneration information can be accomplished by collecting cerebral spinal fluid from below the spinal cord with a procedure called a lumbar puncture or LP.” ~Dr. Carey Gleason

“Over the last 30 years, there has been a steady increase in attention to the disease – both in clinical and research realms. We have gained a deeper understating of the disease, but still have only begun to scratch the surface on prevention and treatment …Research volunteers play a critical role in finding a cure. Being part of an Alzheimer’s disease biomarker study, either by donating cerebrospinal fluid or completing a series of brain scans, is a tremendous gift to the next generation. We need your help as a research participant.” ~Dr. Carey Gleason

“It is essential that study teams recruit a mix of men and women, people of different ages, and people with different socioeconomic, racial and ethnic backgrounds to participate in research. We need diverse populations of research study participants to be part of the solution, so we can find safe and effective treatments that help everyone. We need your help as a research participant.” ~Dr. Carey Gleason