In order to facilitate the request process, the following are statistics compiled for the WRAP cohort. The link to resource requests are at the bottom of this page.
Statistics derived from 05/31/2022 semiannual data freeze.
- Cohort Demographics, APOE, and Cognitive Summary
- Multimodal Biomarker Counts
- MRI
- Lumbar Puncture
- Amyloid PET
- Tau PET
Cohort Demographics and Cognitive Summary
Main Study Visit and Cognitive Status Summary
Statistic | Value |
---|---|
Avg age at 1st cognitive assessments | 54.62 |
StdDev age at 1st cognitive assessments | 6.91 |
Avg age at last cognitive assessments | 65.28 |
StdDev age at last cognitive assessments | 8.53 |
Avg years of cognitive follow ups | 10.66 |
Avg count of cognitive follow ups | 4.48 |
Baseline diagnosis Normal | 1,654.00 |
Baseline diagnosis Dementia | 0.00 |
Baseline diagnosis MCI | 16.00 |
Baseline diagnosis Impaired-Other | 0.00 |
Last (within freeze) diagnosis Normal | 1,573.00 |
Last (within freeze) diagnosis Dementia | 20.00 |
Last (within freeze) diagnosis MCI | 79.00 |
Last (within freeze) diagnosis Impaired-Other | 0.00 |
Primary Race
primary race | count |
---|---|
American Indian/Alaska Native | 0 |
American Indian/Native American | 14 |
Asian | 4 |
Black/African American | 178 |
White/Caucasian | 1,439 |
Spanish/Hispanic | 38 |
Unknown | 19 |
Other | 1 |
Participants with Hispanic Heritage
hispanic people | count |
---|---|
Yes | 38 |
No | 1,636 |
Unknown | 19 |
Sex
sex | count |
---|---|
M | 502 |
F | 1,187 |
null | 3 |
Education
years of education | count |
---|---|
None | 0 |
1-5 (<= grade school) | 133 |
6-8 (<= middle school) | 715 |
9-12 (<= high school) | 578 |
13-14 (<= associates) | 0 |
15-16 (<= bachelors) | 0 |
17-18 (<= masters) | 0 |
19+ (<= phd) | 0 |
missing_999 | 267 |
APOE
apoe combo | count |
---|---|
2/2 | 5 |
2/3 | 124 |
2/4 | 51 |
3/3 | 799 |
3/4 | 492 |
4/4 | 69 |
Null/Null | 152 |
Multimodal Biomarker Counts
Statistic | count |
---|---|
Number of people with LP | 347 |
Number of people with MRI | 641 |
Number of people with Amyloid PET | 370 |
Number of people with Tau PET | 420 |
Number of people with LP & MRI | 300 |
Number of people with LP & Amyloid PET | 214 |
Number of people with LP & Tau PET | 240 |
Number of people with MRI & Amyloid PET | 367 |
Number of people with MRI & Tau PET | 413 |
Number of people with Amyloid PET & Tau PET | 368 |
Number of people with LP & MRI & Amyloid PET | 213 |
Number of people with LP & MRI & Tau PET | 236 |
Number of people with LP & Amyloid PET & Tau PET | 212 |
Number of people with MRI & Amyloid PET & Tau PET | 365 |
Number of people with LP & MRI & Amyloid PET & Tau PET | 211 |
Summary statistics for participants with MRI
WRAP MRI
Number of MRI Assessments | Number of Participants | Avg Yrs Between Assessments | Avg Yrs of Assessments |
---|---|---|---|
>= 1 | 641 | 1.81 | 4.23 |
>= 2 | 416 | 2.79 | 6.52 |
>= 3 | 277 | 2.84 | 8.44 |
>= 4 | 183 | 2.40 | 8.97 |
>= 5 | 95 | 1.97 | 9.32 |
>= 6 | 54 | 1.83 | 9.89 |
Demographic and Cognitive Summary
Statistic | Value |
---|---|
Avg age at 1st cognitive assessments | 54 |
StdDev age at 1st cognitive assessments | 6 |
Avg age at last cognitive assessments | 67 |
StdDev age at last cognitive assessments | 7 |
Avg years of cognitive follow ups | 13 |
Avg count of cognitive follow ups | 5 |
Baseline diagnosis Normal | 635 |
Baseline diagnosis Dementia | 0 |
Baseline diagnosis MCI | 5 |
Baseline diagnosis Impaired-Other | 0 |
Last (within freeze) diagnosis Normal | 604 |
Last (within freeze) diagnosis Dementia | 7 |
Last (within freeze) diagnosis MCI | 30 |
Last (within freeze) diagnosis Impaired-Other | 0 |
Summary statistics for participants with LP
Number of LP Assessments | Number of Participants | Avg Yrs Between Assessments | Avg Yrs of Assessments |
---|---|---|---|
>= 1 | 347 | 1.36 | 2.87 |
>= 2 | 175 | 2.69 | 5.69 |
>= 3 | 109 | 2.55 | 7.36 |
>= 4 | 71 | 2.43 | 8.32 |
>= 5 | 30 | 2.27 | 9.26 |
>= 6 | 2 | 1.89 | 10.25 |
Demographic and Cognitive Summary
Statistic | Value |
---|---|
Avg age at 1st cognitive assessments | 54 |
StdDev age at 1st cognitive assessments | 6 |
Avg age at last cognitive assessments | 67 |
StdDev age at last cognitive assessments | 7 |
Avg years of cognitive follow ups | 13 |
Avg count of cognitive follow ups | 5 |
Baseline diagnosis Normal | 344 |
Baseline diagnosis Dementia | 0 |
Baseline diagnosis MCI | 3 |
Baseline diagnosis Impaired-Other | 0 |
Last (within freeze) diagnosis Normal | 321 |
Last (within freeze) diagnosis Dementia | 4 |
Last (within freeze) diagnosis MCI | 22 |
Last (within freeze) diagnosis Impaired-Other | 0 |
Summary statistics for participants with Amyloid PET
Number of Amyloid PET Assessments | Number of Participants | Avg Yrs Between Assessments | Avg Yrs of Assessments |
---|---|---|---|
>= 1 | 420 | 1.56 | 3.36 |
>= 2 | 213 | 3.07 | 6.63 |
>= 3 | 137 | 3.26 | 8.78 |
>= 4 | 94 | 2.96 | 9.22 |
>= 5 | 13 | 2.37 | 9.66 |
>= 6 | 1 | 2.17 | 10.85 |
Demographic and Cognitive Summary
Statistic | Value |
---|---|
Avg age at 1st cognitive assessments | 54.76 |
StdDev age at 1st cognitive assessments | 7.10 |
Avg age at last cognitive assessments | 68.53 |
StdDev age at last cognitive assessments | 7.11 |
Avg years of cognitive follow ups | 13.76 |
Avg count of cognitive follow ups | 5.86 |
Baseline diagnosis Normal | 366.00 |
Baseline diagnosis Dementia | 0.00 |
Baseline diagnosis MCI | 3.00 |
Baseline diagnosis Impaired-Other | 0.00 |
Last (within freeze) diagnosis Normal | 344.00 |
Last (within freeze) diagnosis Dementia | 4.00 |
Last (within freeze) diagnosis MCI | 21.00 |
Last (within freeze) diagnosis Impaired-Other | 0.00 |
Summary statistics for participants with Tau PET
Number of Tau PET Assessments | Number of Participants | Avg Yrs Between Assessments | Avg Yrs of Assessments |
---|---|---|---|
>= 1 | 370 | 0.91 | 0.93 |
>= 2 | 139 | 2.42 | 2.48 |
>= 3 | 6 | 1.57 | 3.15 |
>= 4 | 0 | 0.00 | 0.00 |
>= 5 | 0 | 0.00 | 0.00 |
>= 6 | 0 | 0.00 | 0.00 |
Demographic and Cognitive Summary
Statistic | Value |
---|---|
Avg age at 1st cognitive assessments | 54 |
StdDev age at 1st cognitive assessments | 7 |
Avg age at last cognitive assessments | 68 |
StdDev age at last cognitive assessments | 7 |
Avg years of cognitive follow ups | 13 |
Avg count of cognitive follow ups | 5 |
Baseline diagnosis Normal | 416 |
Baseline diagnosis Dementia | 0 |
Baseline diagnosis MCI | 3 |
Baseline diagnosis Impaired-Other | 0 |
Last (within freeze) diagnosis Normal | 387 |
Last (within freeze) diagnosis Dementia | 7 |
Last (within freeze) diagnosis MCI | 25 |
Last (within freeze) diagnosis Impaired-Other | 0 |
For scientists interested in WRAP resources
WRAP Application for Resources
Your data request will be taken in consideration by the WRAP Science Executive Committee. You will be notified within 4-6 weeks regarding the status of your application.
For scientists interested in Wisconsin Alzheimer’s Disease Research Center (ADRC) resources
For internal candidates requesting data or images for a project originating within Wisconsin ADRC or WRAP
Your resource request(s) will be taken into consideration by the applicable Science Executive Committee. You will be notified within 4 to 6 weeks regarding the status of your application. The Committee will not provide a written evaluation of proposals. A letter indicating the Committee’s decision to support or not support the proposed request will be provided to the applicant, along with any special instructions and/or requirements that must be met before resources will be released.