In order to facilitate the request process, the following are statistics compiled for the WRAP cohort.
Statistics derived from 05/31/2021 semiannual data freeze.
- Cohort Demographics, APOE, and Cognitive Summary
- Multimodal Biomarker Counts
- MRI
- Lumbar Puncture
- Amyloid PET
- Tau PET
Cohort Demographics and Cognitive Summary
Main Study Visit and Cognitive Status Summary
Statistic | Value |
---|---|
Avg age at 1st cognitive assessments | 54.59 |
StdDev age at 1st cognitive assessments | 6.93 |
Avg age at last cognitive assessments | 64.49 |
StdDev age at last cognitive assessments | 8.25 |
Avg years of cognitive follow ups | 9.90 |
Avg count of cognitive follow ups | 4.21 |
Baseline diagnosis Normal | 1,625.00 |
Baseline diagnosis Dementia | 0.00 |
Baseline diagnosis MCI | 12.00 |
Baseline diagnosis Impaired-Other | 19.00 |
Last (within freeze) diagnosis Normal | 1,563.00 |
Last (within freeze) diagnosis Dementia | 17.00 |
Last (within freeze) diagnosis MCI | 55.00 |
Last (within freeze) diagnosis Impaired-Other | 21.00 |
Primary Race
primary race | count |
---|---|
American Indian or Alaska Native | 14 |
Asian | 4 |
Black or African American | 177 |
White | 1,439 |
Unknown | 20 |
Other | 39 |
Participants with Hispanic Heritage
hispanic heritage | count |
---|---|
Yes | 38 |
No | 1,635 |
Unknown | 20 |
Sex
sex | count |
---|---|
M | 503 |
F | 1,186 |
null | 3 |
Education
years of education | count |
---|---|
None | 0 |
1-5 (<= grade school) | 0 |
6-8 (<= middle school) | 0 |
9-12 (<= high school) | 254 |
13-14 (<= associates) | 308 |
15-16 (<= bachelors) | 284 |
17-18 (<= masters) | 482 |
19+ (<= phd) | 88 |
missing_999 | 277 |
APOE
apoe combo | count |
---|---|
2/2 | 5 |
2/3 | 124 |
2/4 | 51 |
3/3 | 799 |
3/4 | 492 |
4/4 | 69 |
Null/Null | 152 |
Multimodal Biomarker Counts
Statistic | count |
---|---|
Number of people with LP | 270 |
Number of people with MRI | 621 |
Number of people with Amyloid PET | 383 |
Number of people with Tau PET | 330 |
Number of people with LP & MRI | 267 |
Number of people with LP & Amyloid PET | 209 |
Number of people with LP & Tau PET | 180 |
Number of people with MRI & Amyloid PET | 378 |
Number of people with MRI & Tau PET | 329 |
Number of people with Amyloid PET & Tau PET | 328 |
Number of people with LP & MRI & Amyloid PET | 206 |
Number of people with LP & MRI & Tau PET | 180 |
Number of people with LP & Amyloid PET & Tau PET | 178 |
Number of people with MRI & Amyloid PET & Tau PET | 327 |
Number of people with LP & MRI & Amyloid PET & Tau PET | 178 |
Summary statistics for participants with MRI
WRAP MRI
Number of MRI Assessments | Number of Participants | Avg Yrs Between Assessments | Avg Yrs of Assessments |
---|---|---|---|
>= 1 | 569 | 1.81 | 3.82 |
>= 2 | 369 | 2.78 | 5.90 |
>= 3 | 253 | 2.74 | 7.28 |
>= 4 | 132 | 2.15 | 7.76 |
>= 5 | 72 | 1.82 | 7.88 |
>= 6 | 23 | 1.64 | 8.38 |
Demographic and Cognitive Summary
Statistic | Value |
---|---|
Avg age at 1st cognitive assessments | 54 |
StdDev age at 1st cognitive assessments | 6 |
Avg age at last cognitive assessments | 66 |
StdDev age at last cognitive assessments | 7 |
Avg years of cognitive follow ups | 11 |
Avg count of cognitive follow ups | 5 |
Baseline diagnosis Normal | 613 |
Baseline diagnosis Dementia | 0 |
Baseline diagnosis MCI | 4 |
Baseline diagnosis Impaired-Other | 1 |
Last (within freeze) diagnosis Normal | 589 |
Last (within freeze) diagnosis Dementia | 5 |
Last (within freeze) diagnosis MCI | 20 |
Last (within freeze) diagnosis Impaired-Other | 3 |
Summary statistics for participants with LP
Number of LP Assessments | Number of Participants | Avg Yrs Between Assessments | Avg Yrs of Assessments |
---|---|---|---|
>= 1 | 270 | 1.27 | 2.46 |
>= 2 | 134 | 2.56 | 4.95 |
>= 3 | 89 | 2.42 | 6.02 |
>= 4 | 46 | 2.19 | 6.66 |
>= 5 | 2 | 1.87 | 7.48 |
>= 6 | 0 | 0.00 | 0.00 |
Demographic and Cognitive Summary
Statistic | Value |
---|---|
Avg age at 1st cognitive assessments | 54 |
StdDev age at 1st cognitive assessments | 6 |
Avg age at last cognitive assessments | 66 |
StdDev age at last cognitive assessments | 7 |
Avg years of cognitive follow ups | 12 |
Avg count of cognitive follow ups | 5 |
Baseline diagnosis Normal | 268 |
Baseline diagnosis Dementia | 0 |
Baseline diagnosis MCI | 3 |
Baseline diagnosis Impaired-Other | 0 |
Last (within freeze) diagnosis Normal | 259 |
Last (within freeze) diagnosis Dementia | 2 |
Last (within freeze) diagnosis MCI | 9 |
Last (within freeze) diagnosis Impaired-Other | 0 |
Summary statistics for participants with Amyloid PET
Number of Amyloid PET Assessments | Number of Participants | Avg Yrs Between Assessments | Avg Yrs of Assessments |
---|---|---|---|
>= 1 | 383 | 1.69 | 3.45 |
>= 2 | 201 | 3.23 | 6.58 |
>= 3 | 132 | 3.23 | 8.33 |
>= 4 | 78 | 2.88 | 8.91 |
>= 5 | 8 | 2.25 | 9.52 |
>= 6 | 2 | 2.06 | 10.31 |
Demographic and Cognitive Summary
Statistic | Value |
---|---|
Avg age at 1st cognitive assessments | 54.83 |
StdDev age at 1st cognitive assessments | 6.76 |
Avg age at last cognitive assessments | 67.37 |
StdDev age at last cognitive assessments | 6.81 |
Avg years of cognitive follow ups | 12.54 |
Avg count of cognitive follow ups | 5.40 |
Baseline diagnosis Normal | 380.00 |
Baseline diagnosis Dementia | 0.00 |
Baseline diagnosis MCI | 2.00 |
Baseline diagnosis Impaired-Other | 0.00 |
Last (within freeze) diagnosis Normal | 361.00 |
Last (within freeze) diagnosis Dementia | 5.00 |
Last (within freeze) diagnosis MCI | 14.00 |
Last (within freeze) diagnosis Impaired-Other | 2.00 |
Summary statistics for participants with Tau PET
Number of Tau PET Assessments | Number of Participants | Avg Yrs Between Assessments | Avg Yrs of Assessments |
---|---|---|---|
>= 1 | 330 | 0.79 | 0.80 |
>= 2 | 110 | 2.36 | 2.41 |
>= 3 | 4 | 1.34 | 2.68 |
>= 4 | 0 | 0.00 | 0.00 |
>= 5 | 0 | 0.00 | 0.00 |
>= 6 | 0 | 0.00 | 0.00 |
Demographic and Cognitive Summary
Statistic | Value |
---|---|
Avg age at 1st cognitive assessments | 54 |
StdDev age at 1st cognitive assessments | 6 |
Avg age at last cognitive assessments | 67 |
StdDev age at last cognitive assessments | 6 |
Avg years of cognitive follow ups | 12 |
Avg count of cognitive follow ups | 5 |
Baseline diagnosis Normal | 328 |
Baseline diagnosis Dementia | 0 |
Baseline diagnosis MCI | 1 |
Baseline diagnosis Impaired-Other | 0 |
Last (within freeze) diagnosis Normal | 313 |
Last (within freeze) diagnosis Dementia | 2 |
Last (within freeze) diagnosis MCI | 12 |
Last (within freeze) diagnosis Impaired-Other | 2 |
For scientists interested in WRAP resources
WRAP Application for Resources
Your data request will be taken in consideration by the WRAP Science Executive Committee. You will be notified within 4-6 weeks regarding the status of your application.
For scientists interested in Wisconsin Alzheimer’s Disease Research Center (ADRC) resources
For internal candidates requesting data or images for a project originating within Wisconsin ADRC or WRAP
Your resource request(s) will be taken into consideration by the applicable Science Executive Committee. You will be notified within 4 to 6 weeks regarding the status of your application. The Committee will not provide a written evaluation of proposals. A letter indicating the Committee’s decision to support or not support the proposed request will be provided to the applicant, along with any special instructions and/or requirements that must be met before resources will be released.