Data Requests

In order to facilitate the request process, the following are statistics compiled for the WRAP cohort.

Statistics derived from 05/31/2021 semiannual data freeze.

Cohort Demographics and Cognitive Summary

Main Study Visit and Cognitive Status Summary

Statistic	Value
Avg age at 1st cognitive assessments	54.59
StdDev age at 1st cognitive assessments	6.93
Avg age at last cognitive assessments	64.49
StdDev age at last cognitive assessments	8.25
Avg years of cognitive follow ups	9.90
Avg count of cognitive follow ups	4.21
Baseline diagnosis Normal	1,625.00
Baseline diagnosis Dementia	0.00
Baseline diagnosis MCI	12.00
Baseline diagnosis Impaired-Other	19.00
Last (within freeze) diagnosis Normal	1,563.00
Last (within freeze) diagnosis Dementia	17.00
Last (within freeze) diagnosis MCI	55.00
Last (within freeze) diagnosis Impaired-Other	21.00

Primary Race

primary race	count
American Indian or Alaska Native	14
Asian	4
Black or African American	177
White	1,439
Unknown	20
Other	39

Participants with Hispanic Heritage

hispanic heritage	count
Yes	38
No	1,635
Unknown	20

Sex

sex	count
M	503
F	1,186
null	3

Education

years of education	count
None	0
1-5 (<= grade school)	0
6-8 (<= middle school)	0
9-12 (<= high school)	254
13-14 (<= associates)	308
15-16 (<= bachelors)	284
17-18 (<= masters)	482
19+ (<= phd)	88
missing_999	277

APOE

apoe combo	count
2/2	5
2/3	124
2/4	51
3/3	799
3/4	492
4/4	69
Null/Null	152

Multimodal Biomarker Counts

Statistic	count
Number of people with LP	270
Number of people with MRI	621
Number of people with Amyloid PET	383
Number of people with Tau PET	330
Number of people with LP & MRI	267
Number of people with LP & Amyloid PET	209
Number of people with LP & Tau PET	180
Number of people with MRI & Amyloid PET	378
Number of people with MRI & Tau PET	329
Number of people with Amyloid PET & Tau PET	328
Number of people with LP & MRI & Amyloid PET	206
Number of people with LP & MRI & Tau PET	180
Number of people with LP & Amyloid PET & Tau PET	178
Number of people with MRI & Amyloid PET & Tau PET	327
Number of people with LP & MRI & Amyloid PET & Tau PET	178

Summary statistics for participants with MRI

WRAP MRI

Number of MRI Assessments	Number of Participants	Avg Yrs Between Assessments	Avg Yrs of Assessments
>= 1	569	1.81	3.82
>= 2	369	2.78	5.90
>= 3	253	2.74	7.28
>= 4	132	2.15	7.76
>= 5	72	1.82	7.88
>= 6	23	1.64	8.38

Demographic and Cognitive Summary

Statistic	Value
Avg age at 1st cognitive assessments	54
StdDev age at 1st cognitive assessments	6
Avg age at last cognitive assessments	66
StdDev age at last cognitive assessments	7
Avg years of cognitive follow ups	11
Avg count of cognitive follow ups	5
Baseline diagnosis Normal	613
Baseline diagnosis Dementia	0
Baseline diagnosis MCI	4
Baseline diagnosis Impaired-Other	1
Last (within freeze) diagnosis Normal	589
Last (within freeze) diagnosis Dementia	5
Last (within freeze) diagnosis MCI	20
Last (within freeze) diagnosis Impaired-Other	3

Summary statistics for participants with LP

Number of LP Assessments	Number of Participants	Avg Yrs Between Assessments	Avg Yrs of Assessments
>= 1	270	1.27	2.46
>= 2	134	2.56	4.95
>= 3	89	2.42	6.02
>= 4	46	2.19	6.66
>= 5	2	1.87	7.48
>= 6	0	0.00	0.00

Demographic and Cognitive Summary

Statistic	Value
Avg age at 1st cognitive assessments	54
StdDev age at 1st cognitive assessments	6
Avg age at last cognitive assessments	66
StdDev age at last cognitive assessments	7
Avg years of cognitive follow ups	12
Avg count of cognitive follow ups	5
Baseline diagnosis Normal	268
Baseline diagnosis Dementia	0
Baseline diagnosis MCI	3
Baseline diagnosis Impaired-Other	0
Last (within freeze) diagnosis Normal	259
Last (within freeze) diagnosis Dementia	2
Last (within freeze) diagnosis MCI	9
Last (within freeze) diagnosis Impaired-Other	0

Summary statistics for participants with Amyloid PET

Number of Amyloid PET Assessments	Number of Participants	Avg Yrs Between Assessments	Avg Yrs of Assessments
>= 1	383	1.69	3.45
>= 2	201	3.23	6.58
>= 3	132	3.23	8.33
>= 4	78	2.88	8.91
>= 5	8	2.25	9.52
>= 6	2	2.06	10.31

Demographic and Cognitive Summary

Statistic	Value
Avg age at 1st cognitive assessments	54.83
StdDev age at 1st cognitive assessments	6.76
Avg age at last cognitive assessments	67.37
StdDev age at last cognitive assessments	6.81
Avg years of cognitive follow ups	12.54
Avg count of cognitive follow ups	5.40
Baseline diagnosis Normal	380.00
Baseline diagnosis Dementia	0.00
Baseline diagnosis MCI	2.00
Baseline diagnosis Impaired-Other	0.00
Last (within freeze) diagnosis Normal	361.00
Last (within freeze) diagnosis Dementia	5.00
Last (within freeze) diagnosis MCI	14.00
Last (within freeze) diagnosis Impaired-Other	2.00

Summary statistics for participants with Tau PET

Number of Tau PET Assessments	Number of Participants	Avg Yrs Between Assessments	Avg Yrs of Assessments
>= 1	330	0.79	0.80
>= 2	110	2.36	2.41
>= 3	4	1.34	2.68
>= 4	0	0.00	0.00
>= 5	0	0.00	0.00
>= 6	0	0.00	0.00

Demographic and Cognitive Summary

Statistic	Value
Avg age at 1st cognitive assessments	54
StdDev age at 1st cognitive assessments	6
Avg age at last cognitive assessments	67
StdDev age at last cognitive assessments	6
Avg years of cognitive follow ups	12
Avg count of cognitive follow ups	5
Baseline diagnosis Normal	328
Baseline diagnosis Dementia	0
Baseline diagnosis MCI	1
Baseline diagnosis Impaired-Other	0
Last (within freeze) diagnosis Normal	313
Last (within freeze) diagnosis Dementia	2
Last (within freeze) diagnosis MCI	12
Last (within freeze) diagnosis Impaired-Other	2

For scientists interested in WRAP resources

WRAP Application for Resources

Your data request will be taken in consideration by the WRAP Science Executive Committee. You will be notified within 4-6 weeks regarding the status of your application.

For scientists interested in Wisconsin Alzheimer’s Disease Research Center (ADRC) resources

ADRC Application for Resources

For internal candidates requesting data or images for a project originating within Wisconsin ADRC or WRAP

UP Application for Resources

Your resource request(s) will be taken into consideration by the applicable Science Executive Committee. You will be notified within 4 to 6 weeks regarding the status of your application. The Committee will not provide a written evaluation of proposals. A letter indicating the Committee’s decision to support or not support the proposed request will be provided to the applicant, along with any special instructions and/or requirements that must be met before resources will be released.