Data Requests

In order to facilitate the request process, the following are statistics compiled for the WRAP cohort.

Statistics derived from 05/31/2022 semiannual data freeze.

Cohort Demographics and Cognitive Summary

Main Study Visit and Cognitive Status Summary

Statistic	Value
Avg age at 1st cognitive assessments	54.62
StdDev age at 1st cognitive assessments	6.91
Avg age at last cognitive assessments	65.28
StdDev age at last cognitive assessments	8.53
Avg years of cognitive follow ups	10.66
Avg count of cognitive follow ups	4.48
Baseline diagnosis Normal	1,654.00
Baseline diagnosis Dementia	0.00
Baseline diagnosis MCI	16.00
Baseline diagnosis Impaired-Other	0.00
Last (within freeze) diagnosis Normal	1,573.00
Last (within freeze) diagnosis Dementia	20.00
Last (within freeze) diagnosis MCI	79.00
Last (within freeze) diagnosis Impaired-Other	0.00

Primary Race

primary race	count
American Indian/Alaska Native	0
American Indian/Native American	14
Asian	4
Black/African American	178
White/Caucasian	1,439
Spanish/Hispanic	38
Unknown	19
Other	1

Participants with Hispanic Heritage

hispanic people	count
Yes	38
No	1,636
Unknown	19

Sex

sex	count
M	502
F	1,187
null	3

Education

years of education	count
None	0
1-5 (<= grade school)	133
6-8 (<= middle school)	715
9-12 (<= high school)	578
13-14 (<= associates)	0
15-16 (<= bachelors)	0
17-18 (<= masters)	0
19+ (<= phd)	0
missing_999	267

APOE

apoe combo	count
2/2	5
2/3	124
2/4	51
3/3	799
3/4	492
4/4	69
Null/Null	152

Multimodal Biomarker Counts

Statistic	count
Number of people with LP	347
Number of people with MRI	641
Number of people with Amyloid PET	370
Number of people with Tau PET	420
Number of people with LP & MRI	300
Number of people with LP & Amyloid PET	214
Number of people with LP & Tau PET	240
Number of people with MRI & Amyloid PET	367
Number of people with MRI & Tau PET	413
Number of people with Amyloid PET & Tau PET	368
Number of people with LP & MRI & Amyloid PET	213
Number of people with LP & MRI & Tau PET	236
Number of people with LP & Amyloid PET & Tau PET	212
Number of people with MRI & Amyloid PET & Tau PET	365
Number of people with LP & MRI & Amyloid PET & Tau PET	211

Summary statistics for participants with MRI

WRAP MRI

Number of MRI Assessments	Number of Participants	Avg Yrs Between Assessments	Avg Yrs of Assessments
>= 1	641	1.81	4.23
>= 2	416	2.79	6.52
>= 3	277	2.84	8.44
>= 4	183	2.40	8.97
>= 5	95	1.97	9.32
>= 6	54	1.83	9.89

Demographic and Cognitive Summary

Statistic	Value
Avg age at 1st cognitive assessments	54
StdDev age at 1st cognitive assessments	6
Avg age at last cognitive assessments	67
StdDev age at last cognitive assessments	7
Avg years of cognitive follow ups	13
Avg count of cognitive follow ups	5
Baseline diagnosis Normal	635
Baseline diagnosis Dementia	0
Baseline diagnosis MCI	5
Baseline diagnosis Impaired-Other	0
Last (within freeze) diagnosis Normal	604
Last (within freeze) diagnosis Dementia	7
Last (within freeze) diagnosis MCI	30
Last (within freeze) diagnosis Impaired-Other	0

Summary statistics for participants with LP

Number of LP Assessments	Number of Participants	Avg Yrs Between Assessments	Avg Yrs of Assessments
>= 1	347	1.36	2.87
>= 2	175	2.69	5.69
>= 3	109	2.55	7.36
>= 4	71	2.43	8.32
>= 5	30	2.27	9.26
>= 6	2	1.89	10.25

Demographic and Cognitive Summary

Statistic	Value
Avg age at 1st cognitive assessments	54
StdDev age at 1st cognitive assessments	6
Avg age at last cognitive assessments	67
StdDev age at last cognitive assessments	7
Avg years of cognitive follow ups	13
Avg count of cognitive follow ups	5
Baseline diagnosis Normal	344
Baseline diagnosis Dementia	0
Baseline diagnosis MCI	3
Baseline diagnosis Impaired-Other	0
Last (within freeze) diagnosis Normal	321
Last (within freeze) diagnosis Dementia	4
Last (within freeze) diagnosis MCI	22
Last (within freeze) diagnosis Impaired-Other	0

Summary statistics for participants with Amyloid PET

Number of Amyloid PET Assessments	Number of Participants	Avg Yrs Between Assessments	Avg Yrs of Assessments
>= 1	420	1.56	3.36
>= 2	213	3.07	6.63
>= 3	137	3.26	8.78
>= 4	94	2.96	9.22
>= 5	13	2.37	9.66
>= 6	1	2.17	10.85

Demographic and Cognitive Summary

Statistic	Value
Avg age at 1st cognitive assessments	54.76
StdDev age at 1st cognitive assessments	7.10
Avg age at last cognitive assessments	68.53
StdDev age at last cognitive assessments	7.11
Avg years of cognitive follow ups	13.76
Avg count of cognitive follow ups	5.86
Baseline diagnosis Normal	366.00
Baseline diagnosis Dementia	0.00
Baseline diagnosis MCI	3.00
Baseline diagnosis Impaired-Other	0.00
Last (within freeze) diagnosis Normal	344.00
Last (within freeze) diagnosis Dementia	4.00
Last (within freeze) diagnosis MCI	21.00
Last (within freeze) diagnosis Impaired-Other	0.00

Summary statistics for participants with Tau PET

Number of Tau PET Assessments	Number of Participants	Avg Yrs Between Assessments	Avg Yrs of Assessments
>= 1	370	0.91	0.93
>= 2	139	2.42	2.48
>= 3	6	1.57	3.15
>= 4	0	0.00	0.00
>= 5	0	0.00	0.00
>= 6	0	0.00	0.00

Demographic and Cognitive Summary

Statistic	Value
Avg age at 1st cognitive assessments	54
StdDev age at 1st cognitive assessments	7
Avg age at last cognitive assessments	68
StdDev age at last cognitive assessments	7
Avg years of cognitive follow ups	13
Avg count of cognitive follow ups	5
Baseline diagnosis Normal	416
Baseline diagnosis Dementia	0
Baseline diagnosis MCI	3
Baseline diagnosis Impaired-Other	0
Last (within freeze) diagnosis Normal	387
Last (within freeze) diagnosis Dementia	7
Last (within freeze) diagnosis MCI	25
Last (within freeze) diagnosis Impaired-Other	0

For scientists interested in WRAP resources

WRAP Application for Resources

Your data request will be taken in consideration by the WRAP Science Executive Committee. You will be notified within 4-6 weeks regarding the status of your application.

For scientists interested in Wisconsin Alzheimer’s Disease Research Center (ADRC) resources

ADRC Application for Resources

For internal candidates requesting data or images for a project originating within Wisconsin ADRC or WRAP

UP Application for Resources

Your resource request(s) will be taken into consideration by the applicable Science Executive Committee. You will be notified within 4 to 6 weeks regarding the status of your application. The Committee will not provide a written evaluation of proposals. A letter indicating the Committee’s decision to support or not support the proposed request will be provided to the applicant, along with any special instructions and/or requirements that must be met before resources will be released.