Subjective memory complaints, cortical thinning, and cognitive dysfunction in middle-aged adults at risk for AD.

Schultz, S., J. Oh, R. Koscik, N. Dowling, C. Gallagher, C. Carlsson, B. Bendlin, A. LaRue, B. Hermann, H. Rowley, S. Asthana, M. Sager, S. Johnson, and O. Okonkwo. “Subjective Memory Complaints, Cortical Thinning, and Cognitive Dysfunction in Middle-Aged Adults at Risk for AD.”. Alzheimer’s & Dementia (Amsterdam, Netherlands), Vol. 1, no. 1, 2015, pp. 33-40.

Subjective memory complaints (SMCs) represent an individual’s perception of subtle changes in memory in the absence of objective impairment in memory. However, it is not fully known whether persons with SMCs harbor brain alterations related to Alzheimer’s disease (AD) or whether they indeed demonstrate poorer cognitive performance.

DOI: 10.1016/j.dadm.2014.11.010

PubMed: 25938132