Self-reported health behaviors and longitudinal cognitive performance in late middle age: Results from the Wisconsin Registry for Alzheimer’s Prevention.

Mueller, K., D. Norton, R. Koscik, M. Morris, E. Jonaitis, L. Clark, T. Fields, S. Allison, S. Berman, S. Kraning, M. Zuelsdorff, O. Okonkwo, N. Chin, C. Carlsson, B. Bendlin, B. Hermann, and S. Johnson. “Self-Reported Health Behaviors and Longitudinal Cognitive Performance in Late Middle Age: Results from the Wisconsin Registry for Alzheimer’s Prevention.”. PloS One, Vol. 15, no. 4, 2020, p. e0221985.

Studies have suggested associations between self-reported engagement in health behaviors and reduced risk of cognitive decline. Most studies explore these relationships using one health behavior, often cross-sectionally or with dementia as the outcome. In this study, we explored whether several individual self-reported health behaviors were associated with cognitive decline when considered simultaneously, using data from the Wisconsin Registry for Alzheimer’s Prevention (WRAP), an Alzheimer’s disease risk-enriched cohort who were non-demented and in late midlife at baseline.

DOI: 10.1371/journal.pone.0221985

PubMed: 32324741