Neurogranin, a synaptic protein, is associated with memory independent of Alzheimer biomarkers.

Casaletto, K., F. Elahi, B. Bettcher, J. Neuhaus, B. Bendlin, S. Asthana, S. Johnson, K. Yaffe, C. Carlsson, K. Blennow, H. Zetterberg, and J. Kramer. “Neurogranin, a Synaptic Protein, Is Associated With Memory Independent of Alzheimer Biomarkers.”. Neurology, Vol. 89, no. 17, 2017, pp. 1782-8.

To determine the association between synaptic functioning as measured via neurogranin in CSF and cognition relative to established Alzheimer disease (AD) biomarkers in neurologically healthy older adults.

DOI: 10.1212/WNL.0000000000004569

PubMed: 28939668