Interaction of amyloid and tau on cortical microstructure in cognitively unimpaired adults.

Vogt, N., J. Hunt, N. Adluru, Y. Ma, H. Van, D. Iii, S. Kecskemeti, N. Chin, C. Carlsson, S. Asthana, S. Johnson, G. Kollmorgen, R. Batrla, N. Wild, K. Buck, H. Zetterberg, A. Alexander, K. Blennow, and B. Bendlin. “Interaction of Amyloid and Tau on Cortical Microstructure in Cognitively Unimpaired Adults.”. Alzheimer’s & Dementia : The Journal of the Alzheimer’s Association, 2021.

Neurite orientation dispersion and density imaging (NODDI), a multi-compartment diffusion-weighted imaging (DWI) model, may be useful for detecting early cortical microstructural alterations in Alzheimer’s disease prior to cognitive impairment.

DOI: 10.1002/alz.12364

PubMed: 33984184