Gleason, C., T. Schmitz, T. Hess, R. Koscik, M. Trivedi, M. Ries, C. Carlsson, M. Sager, S. Asthana, and S. Johnson. “Hormone Effects on FMRI and Cognitive Measures of Encoding: Importance of Hormone Preparation.”. Neurology, Vol. 67, no. 11, 2006, pp. 2039-41.
We compared fMRI and cognitive data from nine hormone therapy (HT)-naive women with data from women exposed to either opposed conjugated equine estrogens (CEE) (n = 10) or opposed estradiol (n = 4). Exposure to either form of HT was associated with healthier fMRI response; however, CEE-exposed women exhibited poorer memory performance than either HT-naive or estradiol-exposed subjects. These preliminary findings emphasize the need to characterize differential neural effects of various HTs.
DOI: 10.1212/01.wnl.0000247277.81400.43
PubMed: 17159116