Merluzzi, A., N. Vogt, D. Norton, E. Jonaitis, L. Clark, C. Carlsson, S. Johnson, S. Asthana, K. Blennow, H. Zetterberg, and B. Bendlin. “Differential Effects of Neurodegeneration Biomarkers on Subclinical Cognitive Decline.”. Alzheimer’s & Dementia (New York, N. Y.), Vol. 5, 2019, pp. 129-38.
Neurodegeneration appears to be the biological mechanism most proximate to cognitive decline in Alzheimer’s disease. We test whether t-tau and alternative biomarkers of neurodegeneration-neurogranin and neurofilament light protein (NFL)-add value in predicting subclinical cognitive decline.
DOI: 10.1016/j.trci.2019.02.004
PubMed: 31011623