Cardiorespiratory Fitness Modifies Influence of Sleep Problems on Cerebrospinal Fluid Biomarkers in an At-Risk Cohort.

Law, L., K. Sprecher, R. Dougherty, D. Edwards, R. Koscik, C. Gallagher, C. Carlsson, H. Zetterberg, K. Blennow, S. Asthana, M. Sager, B. Hermann, S. Johnson, D. Cook, B. Bendlin, and O. Okonkwo. “Cardiorespiratory Fitness Modifies Influence of Sleep Problems on Cerebrospinal Fluid Biomarkers in an At-Risk Cohort.”. Journal of Alzheimer’s Disease : JAD, Vol. 69, no. 1, 2019, pp. 111-2.

Previous studies indicate that cardiorespiratory fitness (CRF) and sleep are each favorably associated with Alzheimer’s disease (AD) pathophysiology, including reduced amyloid-β (Aβ) and tau pathology. However, few studies have examined CRF and sleep in the same analysis.

DOI: 10.3233/JAD-180291

PubMed: 30958346