Hypertension and obesity moderate the relationship between β-amyloid and cognitive decline in midlife.

Clark, L., R. Koscik, S. Allison, S. Berman, D. Norton, C. Carlsson, T. Betthauser, B. Bendlin, B. Christian, N. Chin, S. Asthana, and S. Johnson. “Hypertension and Obesity Moderate the Relationship Between β-Amyloid and Cognitive Decline in Midlife.”. Alzheimer’s & Dementia : The Journal of the Alzheimer’s Association, Vol. 15, no. 3, 2019, pp. 418-2.

This study tested if central obesity, hypertension, or depressive symptoms moderated the relationship between β-amyloid (Aβ) and longitudinal cognitive performance in late middle-aged adults enriched for Alzheimer’s disease (AD) risk.

DOI: 10.1016/j.jalz.2018.09.008

PubMed: 30367828